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New bioceramic screw revolutionize setting of complex bone fractures

The German based Fraunhofer Institute has developed a bioceramic screw nail to set complex bone fractures. The screw mail could in the future replace the currently used titanium or steel screws and plates. Advantages of the bioceramic alternative are that it be easily introduced into bone and does not have to be removed. Fraunhofer researchers are presenting the screw nail from November 14-17 at the MEDICA trade fair in Düsseldorf.

The beginning of the ski season is always a hectic period for alpine emergency wards. After treatment, some patients end up with metal components in their bodies, as complex bone fractures are usually set with titanium or steel screws and plates. These must be surgically removed later, often at considerable expense and discomfort to the patient. Sscrews remain in the body can trigger inflammation or allergies in sensitive patients.

Now, researchers from the Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM have partnered with the university hospitals of Giessen-Marburg and Bonn and the University of Bremen to develop a bioceramic implant screw nail. The new biomedical component, dubbed a “scrail,” is made of calcium phosphate, which greatly resembles the composition of bone material. The project was supported by the German Federal Ministry for Education and Research with a million-euro grant.

Reduced risk of damage

In contrast to previous medical screws made from titanium or polymer, the new screw nail will not be screwed into the bone, but rather carefully hammered in. For this reason, researchers have developed a specially shaped thread for the screw nail that allows it to be implemented with a minimum of rotations. It also reduces the risk of damage to tendons and bones.

Where metal component sneed to be removed, the ceramic screw nail integrates into the bone, since the two most used bioceramic materials – calcium phosphate and hydroxyapatite – are very similar to bone material. Polymer screws disintegrate in the body, but the degradation products can cause inflammation. Additionally, after the disintegration, cavities can form in bones, rendering them unstable and more prone to breaking. Ceramic-based screw nails do not disintegrate, but instead bond with the bone. Ideally, they might even accelerate bone growth

Maximum strength greatest challenge

According to Dr. Sebastian Hein from Fraunhofer IFAM, important project tasks included designing the screw nail according to ceramic requirements and hardening it . The greatest challenge for the development team however was attaining the maximum strength of the material, since ceramics are fairly breakable.

The solution: with injection molding technology, researchers pour hydroxyapatite powder into screw nail molds and heat them. Using the right process para-meters delivers components with optimized stability. The procedure is particularly suited to mass production, as it is inexpensive and allows for flexible mold design. Furthermore, hydroxyapatite powder can be used in conjunction with 3D printers, thus enabling the production of patient-specific implants.

Hein believes that the screw nail will soon be ready to use in operations, as calcium phosphate has already been tested for biocompatibility and has been used a material in medical applications for several years. Furthermore, medical tests in sheep have shown that the screw nail could be inserted much more quickly and precisely than standard screws, which was “an effect totally unexpected from our side,” says Hein. As a result, the operation time is shortened and the patient is under anesthetic for less time.

Whixx

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